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SAN FRANCISCO — Billionaire philanthropists are donating $25 million to the University of California, San Francisco toward building a new stem cell research center.

University officials announced the donation today from the Eli and Edythe Broad Foundation.

The money will help fund a $123 million laboratory building to bring all the university’s stem cell research under one roof.

The Broads, who live in Los Angeles, made their wealth in housing and financial services. They have donated hundreds of millions of dollars to disease research.

Last year, the couple pledged $20 million to the stem cell institute at the University of California, Los Angeles. In 2006, they gave $25 million to establish a stem cell center at the University of Southern California.